SCHEMBL7757970

SCHEMBL7757970

CC(C)=CCCCCO[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
ALOX15 P16050 4/20 0.33
SQLE Q14534 3/20 0.33
MEN1 O00255 2/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
UGT1A1 P22309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3332165 0.93
SCHEMBL59251 0.82
SCHEMBL1018000 0.79 KMT2A (0.34) KMT2AALOX15SQLEMEN1CYP3A4
SCHEMBL8078444 0.79 KMT2A (0.50) KMT2AALOX15SQLEMEN1CYP3A4
SCHEMBL8952248 0.76 ALDH1A1 (0.41) KMT2AALDH1A1
SCHEMBL8218809 0.76 ALDH1A1 (0.41) KMT2AALDH1A1
SCHEMBL1017744 0.76 TSHR (0.37) KMT2AALOX15SQLEMEN1CYP3A4
SCHEMBL7979328 0.74 KMT2A (0.42) KMT2AALOX15SQLEMEN1CYP3A4
SCHEMBL4104999 0.73 ALOX15 (0.56) ALOX15CYP3A4ALDH1A1TSHR
SCHEMBL1018001 0.73 KMT2A (0.35) KMT2AALOX15MEN1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6258913-B1 ADDITION-POLYSILOXANE COPOLYMERS WACKER-CHEMIE GMBH (DE) 2001-07-10 US disclosed
EP-0953004-B1 POLYMERIC ORGANOSILICON COMPOUNDS, THEIR PRODUCTION AND USE WACKER CHEMIE GMBH (DE) 2001-04-04 EP disclosed
EP-0953004-A1 POLYMERIC ORGANOSILICON COMPOUNDS, THEIR PRODUCTION AND USE Wacker-Chemie GmbH (DE) 1999-11-03 EP disclosed
WO-1998031727-A1 POLYMERIC ORGANOSILICON COMPOUNDS, THEIR PRODUCTION AND USE WACKER-CHEMIE GMBH (DE) 1998-07-23 WO disclosed