Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705408 | 0.87 | CYP3A4 (0.46) | TDP1CYP3A4TSHRCA1CA2 | |
| SCHEMBL7059564 | 0.81 | CYP3A4 (0.34) | TDP1CYP3A4TSHRATMRECQL | |
| SCHEMBL7758103 | 0.80 | ALDH1A1 (0.36) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL7758151 | 0.80 | TSHR (0.41) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11356150 | 0.79 | TSHR (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4075525 | 0.77 | ALDH1A1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27946508 | 0.77 | TSHR (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL20981460 | 0.77 | HDAC1 (0.41) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL13506382 | 0.74 | TSHR (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL24571120 | 0.74 | CYP2D6 (0.41) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085022-A1 | A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds | Dow Corning Asia, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6060620-A | Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds | DOW CORNING ASIA, LTD. (JP) | 2000-05-09 | — | — | US | disclosed |