Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7758162

CCOP(=S)(S)Oc1ccccc1.N

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPSR1 Q6W5P4 1/20 0.39
LTA4H P09960 1/20 0.38
KCNH2 Q12809 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
SRC P12931 1/20 0.36
POLB P06746 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27534385 0.96 HSD17B10 (0.42) HSD17B10ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL187567 0.84 ALDH1A1 (0.57) HSD17B10ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL1605192 0.84 ALDH1A1 (0.53) HSD17B10ALDH1A1CYP3A4TSHRMAPK1
Ammonia Solution, Strong SCHEMBL7759745 0.83 SRC (0.44) HSD17B10TSHRL3MBTL1LTA4HCA4
SCHEMBL6387607 0.81 LTA4H (0.47) ALDH1A1CYP3A4MAPK1LTA4HKCNH2
SCHEMBL11145176 0.81 LTA4H (0.47) ALDH1A1CYP3A4MAPK1LTA4HKCNH2
SCHEMBL11709724 0.81 LTA4H (0.47) ALDH1A1CYP3A4MAPK1LTA4HKCNH2
SCHEMBL1158054 0.81 SRC (0.46) HSD17B10TSHRL3MBTL1LTA4HCA4
SCHEMBL27782437 0.78 CA4 (0.42) HSD17B10ALDH1A1CYP3A4TSHRMAPK1
Zinc Ion SCHEMBL2973913 0.77 SRC (0.43) HSD17B10TSHRL3MBTL1LTA4HCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214954-B1 HOMO OR COPOLYMERIZING AN OLEFIN WITH POLYMERIZATION CATALYST COMPRISING A TRANSITION METAL COMPOUND, CYCLOPENTADIENYL RING CONTAINING LIGAND AND A CHELATING LIGAND, PRODUCES POLYMER WITH NARROW MOLECULAR WEIGHT DISTRIBUTION AND UNIFORMITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-04-10 US disclosed
EP-0798313-B1 OLEFIN POLYMERIZATION CATALYST ASAHI CHEMICAL IND (JP) 2001-03-21 EP disclosed
EP-0798313-A1 OLEFIN POLYMERIZATION CATALYST Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-10-01 EP disclosed