Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | DPYD | Q12882 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.38 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17687568 | 0.94 | GAA (0.50) | GAADPYDMAPTALDH1A1ATAD2 | |
| SCHEMBL3561548 | 0.92 | DPYD (0.45) | GAADPYDMAPTALDH1A1ATAD2 | |
| SCHEMBL3384992 | 0.72 | KDM3B (0.44) | GAAMAPTALDH1A1CCNE1CDK2 | |
| SCHEMBL22869289 | 0.70 | NT5E (0.49) | GAAMAPTALDH1A1LMNAKDM4C | |
| SCHEMBL3425571 | 0.69 | MAPT (0.36) | GAADPYDMAPTALDH1A1ATAD2 | |
| SCHEMBL22869288 | 0.67 | NT5E (0.49) | GAAALDH1A1LMNACCNE1CDK2 | |
| SCHEMBL28511491 | 0.66 | MAPT (0.38) | GAADPYDMAPTALDH1A1ATAD2 | |
| SCHEMBL30534773 | 0.66 | DPYD (0.36) | GAADPYDMAPTALDH1A1ATAD2 | |
| SCHEMBL19337221 | 0.65 | GAA (0.36) | GAADPYDMAPTALDH1A1ATAD2 | |
| SCHEMBL31618326 | 0.64 | JAK2 (0.36) | CCNE1CDK2CCNT1CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |