Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | DPYD | Q12882 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561548 | 0.69 | DPYD (0.45) | MAPTSMN1; SMN2DPYDALDH1A1GAA | |
| SCHEMBL7758271 | 0.66 | GAA (0.47) | MAPTSMN1; SMN2DPYDALDH1A1GAA | |
| SCHEMBL17687568 | 0.65 | GAA (0.50) | MAPTSMN1; SMN2DPYDALDH1A1GAA | |
| SCHEMBL30534773 | 0.60 | DPYD (0.36) | MAPTSMN1; SMN2DPYDALDH1A1GAA | |
| SCHEMBL8951248 | 0.60 | MAPT (0.44) | MAPTSMN1; SMN2TDP1ALDH1A1GAA | |
| SCHEMBL7744554 | 0.60 | MAPT (0.53) | MAPTSMN1; SMN2TDP1ALDH1A1ERN1 | |
| SCHEMBL3396242 | 0.60 | MAPT (0.53) | MAPTSMN1; SMN2TDP1ALDH1A1GAA | |
| SCHEMBL19337221 | 0.59 | GAA (0.36) | MAPTSMN1; SMN2DPYDALDH1A1GAA | |
| SCHEMBL7598686 | 0.59 | ALDH1A1 (0.49) | MAPTSMN1; SMN2DPYDALDH1A1GAA | |
| SCHEMBL28982471 | 0.59 | MAPT (0.40) | MAPTSMN1; SMN2TDP1ALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113151261-A | Antisense oligonucleotides as inhibitors of TGF-R signaling | 神经视觉医药有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107002082-B | Antisense oligonucleotides as inhibitors of TGF-R signaling | 神经视觉医药有限公司 | 2021-02-02 | — | — | CN | disclosed |