Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020250 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5393044 | 0.81 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL29822834 | 0.81 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL19328513 | 0.79 | KDM4E (0.59) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL70470 | 0.78 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL2237689 | 0.78 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL560243 | 0.78 | CA1 (0.69) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL7759639 | 0.77 | TSHR (0.63) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL728817 | 0.76 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL2253933 | 0.76 | MAPT (0.62) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056982-A1 | VITAMIN D-DERIVATIVES AND THEIR USE IN TREATING OSTEOPOROSIS AND RELATED BONE DISORDERS | LEO PHARMA A/S (DK) | 2001-08-09 | — | — | WO | disclosed |