SCHEMBL70470

SCHEMBL70470

COC(=O)c1ccc(Cl)c(C(=O)OC)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
MAPT P10636 6/20 0.58
KDM4E B2RXH2 6/20 0.58
HSD17B10 Q99714 2/20 0.58
HPGD P15428 2/20 0.58
GLA P06280 1/20 0.58
GAA P10253 1/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
ATM Q13315 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
LMNA P02545 3/20 0.55
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4657653 0.89 MEN1 (0.56) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL4462421 0.89 ALDH1A1 (0.57) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL1929461 0.89 ALDH1A1 (0.61) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL22082633 0.87 ALDH1A1 (0.51) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL1930540 0.87 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL69263 0.85 KDM4E (0.62) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL17110515 0.84 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL29822834 0.84 ALDH1A1 (0.64) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL5393044 0.84 ALDH1A1 (0.64) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL16709906 0.83 MEN1 (0.48) ALDH1A1MAPTKDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-5118680-A COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US disclosed
EP-0403885-A1 Utilization of 3-hydroxybenzothiophens for combatting endoparasites, new 3-hydroxythiophens and process for their preparation BAYER AG (DE) 1990-12-27 EP disclosed
EP-0017422-B1 THERMOPLASTIC POLYAMIDEIMIDE COPOLYMERS AND METHOD OF PREPARATION TORAY INDUSTRIES, INC. (JP) 1983-11-30 EP disclosed
US-4299945-A HEAT POLYMERIZATION OF AN AROMATIC DIAMINO COMPOUND AND AN AROMATIC TRIBASIC CARBOXYLIC ACID TORAY INDUSTRIES, INC. (JP) 1981-11-10 US disclosed
EP-0017422-A1 Thermoplastic polyamideimide copolymers and method of preparation TORAY INDUSTRIES, INC. (JP) 1980-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALDH1A1 1882/4885MAPT 1923/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.