Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.46 |
| ▸ | PEPD | P12955 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10871680 | 0.98 | DPP4 (0.47) | DPP4DPP8DPP9DPP7PEPD | |
| SCHEMBL15384070 | 0.95 | PEPD (0.50) | DPP4DPP8DPP9DPP7PEPD | |
| SCHEMBL19753428 | 0.95 | PEPD (0.50) | DPP4DPP8DPP9DPP7PEPD | |
| SCHEMBL7290477 | 0.92 | DPP4 (0.48) | DPP4DPP8DPP9DPP7PEPD | |
| SCHEMBL8661714 | 0.85 | DPP7 (0.56) | DPP4DPP8DPP9DPP7PEPD | |
| SCHEMBL10778765 | 0.84 | HDAC1 (0.41) | PEPDMEN1KMT2AGAAITGB3 | |
| SCHEMBL26255931 | 0.80 | TDP1 (0.50) | DPP4DPP8DPP9DPP7TDP1 | |
| SCHEMBL10778685 | 0.80 | PEPD (0.46) | DPP4DPP8DPP9DPP7PEPD | |
| SCHEMBL16921326 | 0.80 | ACE (0.56) | PEPDMEN1KMT2AGAAITGB3 | |
| SCHEMBL16924987 | 0.78 | ITGB3 (0.52) | MEN1KMT2AGAAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068114-A1 | NOVEL PEPTIDES WITH ANTI-HYPERTENSIVE ACTIVITY | MONSANTO COMPANY (US) | 2001-09-20 | — | — | WO | disclosed |
| EP-0877753-A1 | PEPTIDE INHIBITORS OF HEMATOPOIETIC CELL PROLIFERATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (FR) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997028183-A1 | PEPTIDE INHIBITORS OF HEMATOPOIETIC CELL PROLIFERATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (S.C.R.A.S.) (FR) | 1997-08-07 | — | — | WO | disclosed |
| EP-0084941-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-11 | — | — | EP | disclosed |