SCHEMBL8661714

SCHEMBL8661714

CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 9/20 0.56
▸ DPP4 P27487 7/20 0.56
▸ DPP8 Q6V1X1 7/20 0.56
▸ DPP9 Q86TI2 4/20 0.56
▸ FAP Q12884 3/20 0.56
▸ PEPD P12955 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758736 0.85 DPP4 (0.46) DPP7DPP4DPP8DPP9FAP
SCHEMBL10778685 0.84 PEPD (0.46) DPP7DPP4DPP8DPP9FAP
SCHEMBL12420379 0.84 DPP7 (0.60) DPP7DPP4DPP8DPP9FAP
Oxalic Acid SCHEMBL10871680 0.84 DPP4 (0.47) DPP7DPP4DPP8DPP9FAP
SCHEMBL7288661 0.83 ITGB3 (0.58) DPP4DPP8PEPD
SCHEMBL7313646 0.83 ITGB3 (0.58) DPP4DPP8PEPD
SCHEMBL21248247 0.81 DPP7 (0.56) DPP7DPP4DPP8DPP9FAP
SCHEMBL2113409 0.81 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP
SCHEMBL2123083 0.81 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP
SCHEMBL29406923 0.81 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877753-A1 PEPTIDE INHIBITORS OF HEMATOPOIETIC CELL PROLIFERATION SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (FR) 1998-11-18 — — EP disclosed
WO-1997028183-A1 PEPTIDE INHIBITORS OF HEMATOPOIETIC CELL PROLIFERATION SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (S.C.R.A.S.) (FR) 1997-08-07 — — WO disclosed
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