Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 18/20 | 0.48 |
| ▸ | LDHB | P07195 | 9/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008687 | 0.90 | LDHA (0.41) | LDHALDHB | |
| SCHEMBL8010782 | 0.88 | LDHA (0.38) | LDHALDHB | |
| SCHEMBL8010721 | 0.86 | LDHA (0.37) | LDHALDHB | |
| SCHEMBL8007680 | 0.86 | LDHA (0.37) | LDHALDHB | |
| SCHEMBL8011472 | 0.86 | LDHA (0.47) | LDHALDHB | |
| SCHEMBL6604139 | 0.85 | LDHA (0.48) | LDHALDHB | |
| SCHEMBL7999278 | 0.84 | LTA4H (0.39) | LDHA | |
| SCHEMBL6604343 | 0.83 | LDHA (0.48) | LDHALDHBASAH1 | |
| SCHEMBL8702422 | 0.83 | LDHA (0.52) | LDHALDHB | |
| SCHEMBL8416462 | 0.83 | MGAT2 (0.35) | LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | disclosed |
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | disclosed |
| US-6046355-A | TOLUENE-4-THIOSULFONIC ACID S-ESTERS AS CHEMICAL INTERMEDIATES FOR VIRICIDES AND ASPARTYL PROTEASE INHIBITORS; AIDS | WARNER-LAMBERT COMPANY (US) | 2000-04-04 | — | — | US | disclosed |
| EP-0935597-A2 | DIHYDROPYRONES WITH IMPROVED ANTIVIRAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998019997-A2 | DIHYDROPYRONES WITH IMPROVED ANTIVIRAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |