SCHEMBL7758939

SCHEMBL7758939

[CH2]c1ccc(NS(=O)(=O)CCC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.48
LMNA P02545 3/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PGR P06401 1/20 0.48
PTPN5 P54829 1/20 0.47
KDR P35968 2/20 0.46
AURKB Q96GD4 2/20 0.46
PLK4 O00444 1/20 0.46
DCLK1 O15075 1/20 0.46
DAPK3 O43293 1/20 0.46
DYRK3 O43781 1/20 0.46
JAK2 O60674 1/20 0.46
ROCK2 O75116 1/20 0.46
PRKD3 O94806 1/20 0.46
MAP4K4 O95819 1/20 0.46
CDK1 P06493 1/20 0.46
ROS1 P08922 1/20 0.46
PRKACA P17612 1/20 0.46
RPS6KB1 P23443 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7985726 0.89 HPGD (0.59) HPGDLMNAHTTSMN1; SMN2KDR
SCHEMBL9453327 0.86 THRA (0.53) HPGDLMNAHTTSMN1; SMN2KDR
SCHEMBL7988528 0.86 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2PGR
SCHEMBL7761718 0.85 HPGD (0.55) HPGDLMNAHTTSMN1; SMN2PGR
SCHEMBL10191923 0.82 CA1 (0.53) HPGDLMNAHTTSMN1; SMN2PGR
SCHEMBL7761720 0.81 HPGD (0.58) HPGDLMNAHTTSMN1; SMN2PGR
SCHEMBL21024552 0.81 KMT2A (0.54) HPGDLMNAHTTSMN1; SMN2PGR
SCHEMBL4766928 0.81 CA1 (0.52) HPGDLMNAHTTSMN1; SMN2PGR
SCHEMBL255294 0.80 KEAP1 (0.54) HPGDLMNAHTTSMN1; SMN2PGR
Hydrochloric Acid SCHEMBL31111910 0.78 KEAP1 (0.52) HPGDLMNAHTTSMN1; SMN2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-0849626-B1 Colour photographic recording material with improved mechanical properties and improved stability in tropical climates AGFA GEVAERT (BE) 2001-05-23 EP disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed
US-5932402-A ORGANIC YELLOW PYRAZOLONE AND/OR SULFONAMIDE DYE THAT CAN BE DECOLORIZED DURING PROCESSING AGFA-GEVAERT AG (DE) 1999-08-03 US disclosed
US-5776667-A SILVER HALIDE EMULSIONS ON FILM SUPPORTS WITH CYAN, MAGENTA AND YELLOW COUPLERS OF ISOOXAZOLE AGFA AG (DE) 1998-07-07 US disclosed
EP-0849626-A2 Colour photographic recording material with improved mechanical properties and improved stability in tropical climates Agfa-Gevaert AG (DE) 1998-06-24 EP disclosed