Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.58 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185240 | 1.00 | ITGB3 (0.58) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL844471 | 1.00 | ITGB3 (0.58) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL16124609 | 0.96 | ITGB3 (0.57) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL11123914 | 0.95 | CTSL (0.54) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL11123913 | 0.95 | CTSL (0.54) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL16124604 | 0.95 | ITGB3 (0.58) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL9936982 | 0.93 | MME (0.61) | ITGB3ITGA2BACEACE2MME | |
| SCHEMBL15201783 | 0.93 | MME (0.61) | ITGB3ITGA2BACEACE2MME | |
| SCHEMBL3927408 | 0.91 | ACE (0.60) | ITGB3ITGA2BACEACE2MME | |
| SCHEMBL10638413 | 0.91 | ITGB3 (0.67) | ITGB3ITGA2BACEACE2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087935-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065866-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1999-12-23 | — | — | WO | disclosed |
| US-5519025-A | 4-indolylpiperazinyl derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-21 | — | — | US | disclosed |