Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348973 | 1.00 | NTMT1 (0.53) | NTMT1KDM4EHSD17B10SIGMAR1MC4R | |
| Hydrochloric Acid SCHEMBL8344648 | 0.99 | NTMT1 (0.53) | NTMT1KDM4EHSD17B10SIGMAR1MC4R | |
| Hydrochloric Acid SCHEMBL7761849 | 0.99 | NTMT1 (0.53) | NTMT1KDM4EHSD17B10SIGMAR1MC4R | |
| SCHEMBL8343138 | 0.88 | NTMT1 (0.58) | NTMT1KDM4EHSD17B10MC4RMC5R | |
| SCHEMBL7759044 | 0.88 | NTMT1 (0.58) | NTMT1KDM4EHSD17B10MC4RMC5R | |
| Hydrochloric Acid SCHEMBL8349180 | 0.87 | NTMT1 (0.57) | NTMT1KDM4EHSD17B10MC4RMC5R | |
| Hydrochloric Acid SCHEMBL7763503 | 0.87 | NTMT1 (0.57) | NTMT1KDM4EHSD17B10MC4RMC5R | |
| Hydrochloric Acid SCHEMBL7758996 | 0.85 | F2 (0.40) | PLGF2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8348979 | 0.85 | F2 (0.40) | PLGF2PRSS1PRSS2PRSS3 | |
| SCHEMBL8346795 | 0.85 | KDM4E (0.45) | NTMT1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |