SCHEMBL775913

SCHEMBL775913

CCCCCCCC(=O)N[C@@H]1CCC[C@H]1NC(=O)CCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 6/20 0.69
CNR1 P21554 4/20 0.69
CNR2 P34972 4/20 0.69
GNAI3 P08754 1/20 0.57
GNAO1 P09471 1/20 0.57
GNAI1 P63096 1/20 0.57
CCR2 P41597 1/20 0.52
HSP90AA1 P07900 1/20 0.52
MEN1 O00255 1/20 0.52
FAAH O00519 1/20 0.52
MAPK1 P28482 1/20 0.52
KMT2A Q03164 1/20 0.52
NAAA Q02083 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777490 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL16001843 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL776984 0.98 TRPV1 (0.66) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL776430 0.96 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL775515 0.96 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL247278 0.96 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13870525 0.96 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL19963564 0.96 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13870526 0.96 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13949790 0.96 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673998-B2 Polymer compositions with improved cold flow BRIDGESTONE CORPORATION (JP) 2014-03-18 US disclosed
US-20120071583-A1 POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW BRIDGESTONE CORPORATION (JP) 2012-03-22 US disclosed