SCHEMBL776430

SCHEMBL776430

CCCCCCCCCCCC(=O)N[C@@H]1CCCC[C@H]1NC(=O)CCCCCCCCCCC

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 6/20 0.69
CNR1 P21554 4/20 0.69
CNR2 P34972 4/20 0.69
GNAI3 P08754 1/20 0.57
GNAO1 P09471 1/20 0.57
GNAI1 P63096 1/20 0.57
CCR2 P41597 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.55
HSP90AA1 P07900 1/20 0.52
MEN1 O00255 1/20 0.52
FAAH O00519 1/20 0.52
MAPK1 P28482 1/20 0.52
KMT2A Q03164 1/20 0.52
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5152781 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL19963567 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL12555492 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL19963564 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13870526 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13870525 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL247278 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL775515 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13949790 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13701265 1.00 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820146-B2 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2010-10-26 US claimed
EP-1515684-B1 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM OREAL (FR) 2010-05-19 EP claimed
US-20080057011-A1 Composition structured with a polymer containing a heteroatom and an Organogelator L'OREAL S.A., 2008-03-06 US claimed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US claimed
US-6395803-B1 POLYMERIZABLE ACRYLIC MONOMER, FILLER AND AMIDE RHEOLOGICAL MODIFIER; SHRINKAGE INHIBITION, PHYSICAL PROPERTIES, WEAR RESISTANCE KERR CORPORATION 2002-05-28 US claimed
US-20240287261-A1 METHOD FOR PRODUCING POLYMERIC NANOFIBER AGGREGATE, POLYMERIC NANOFIBER AGGREGATE, UNIAXIALLY ORIENTED POLYMERIC NANOFIBER AGGREGATE SUBSTRATE, AND LASER DESORPTION/IONIZATION MASS SPECTROMETRY SUBSTRATE KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2024-08-29 US disclosed
US-20230162883-A1 COMPOSITION AND METHOD UNIV LIVERPOOL (GB) 2023-05-25 US disclosed
EP-2526921-B1 DENTAL RESTORATIVE MATERIAL KERR CORP (US) 2022-12-21 EP disclosed
US-9642782-B2 Dental restorative material KERR CORPORATION (US) 2017-05-09 US disclosed
US-20160128910-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION 2016-05-12 US disclosed
US-9237991-B2 Dental restorative material KERR CORPORATION (US) 2016-01-19 US disclosed
US-20140371342-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION 2014-12-18 US disclosed
US-6726915-B2 DIAMIDE COMPOUNDS RETAINING GOOD COSMETIC PROPERTIES, IN PARTICULAR A CERTAIN LEVEL OF L'OREAL (FR) 2004-04-27 US disclosed
US-20030129211-A9 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides L'OREAL S.A. (FR) 2003-07-10 US disclosed
WO-2003005977-A2 ANTIPERSPIRANT FORMULATIONS UNILEVER PLC (GB) 2003-01-23 WO disclosed
US-20020150602-A1 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides LIVOREIL AUDE (FR) 2002-10-17 US disclosed
US-6410003-B1 ALKYLAMIDES DERIVED FROM TRANS-1,2-DIAMINOCYCLOHEXANE USED AS STRUCTURANTS UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2002-06-25 US disclosed
US-6395803-B1 POLYMERIZABLE ACRYLIC MONOMER, FILLER AND AMIDE RHEOLOGICAL MODIFIER; SHRINKAGE INHIBITION, PHYSICAL PROPERTIES, WEAR RESISTANCE KERR CORPORATION 2002-05-28 US disclosed
US-20020037263-A1 Alkylamides Derived from Trans-1,2-Diaminocyclohexane used as structurants UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC 2002-03-28 US disclosed
EP-1177784-A2 Antiperspirant compositions Unilever Plc (GB) 2002-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080057011-A1 Composition structured with a polymer containing a heteroatom and an Organogelator CUTA, FABP4, PARG TRPV1 1427/4885CNR1 2465/4885CNR2 1690/4885
US-20160128910-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 TRPV1 3032/4885CNR1 4555/4885CNR2 4768/4885
US-20030129211-A9 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides FAAH, HRH1, HRH4 TRPV1 412/4885CNR1 453/4885CNR2 650/4885
US-20020150602-A1 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides FAAH, HRH1, HRH4 TRPV1 412/4885CNR1 453/4885CNR2 650/4885
US-20020037263-A1 Alkylamides Derived from Trans-1,2-Diaminocyclohexane used as structurants SAT1, TAAR1, OPRM1 TRPV1 1257/4885CNR1 57/4885CNR2 134/4885
US-20140371342-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 TRPV1 3032/4885CNR1 4555/4885CNR2 4768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.