SCHEMBL776984

SCHEMBL776984

CCCCCC(=O)N[C@@H]1CCC[C@H]1NC(=O)CCCCC

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 9/20 0.66
CNR1 P21554 7/20 0.66
CNR2 P34972 7/20 0.66
GNAI3 P08754 1/20 0.54
GNAO1 P09471 1/20 0.54
GNAI1 P63096 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
CCR2 P41597 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16001843 0.98 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL775913 0.98 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL777490 0.98 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13870528 0.96 TRPV1 (0.66) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL777541 0.96 TRPV1 (0.66) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL247278 0.94 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL775515 0.94 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL776430 0.94 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL13870526 0.94 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1
SCHEMBL19963564 0.94 TRPV1 (0.69) TRPV1CNR1CNR2GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673998-B2 Polymer compositions with improved cold flow BRIDGESTONE CORPORATION (JP) 2014-03-18 US disclosed
US-20120071583-A1 POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW BRIDGESTONE CORPORATION (JP) 2012-03-22 US disclosed