Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754584 | 1.00 | KMT2A (0.47) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL668867 | 0.87 | TSHR (0.54) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL7760951 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL7759459 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL8106646 | 0.81 | CYSLTR2 (0.35) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL8102311 | 0.81 | CYSLTR2 (0.35) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL25428188 | 0.81 | KMT2A (0.46) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL17197409 | 0.81 | PTPN11 (0.47) | KMT2ATSHRTP53 | |
| SCHEMBL18417204 | 0.80 | TSHR (0.65) | KMT2AALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL19821464 | 0.80 | CA12 (0.47) | KMT2ATSHRLMNATP53CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754675-B1 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 2001-03-21 | — | — | EP | disclosed |
| US-6031015-A | POLYMERIZABLE POLYESTER OF 1-10 REPEATING UNITS BEING MODIFIED ON BOTH ENDS BY A HYDROXYALKYL (METH)ACRYLATE; SHRINKAGE INHIBITION; LOW VISCOSITY; MECHANICAL STRENGTH; CAN INCLUDE MORE FILLER THAN USUAL | IVOCLAR AG (LI) | 2000-02-29 | — | — | US | disclosed |
| EP-0754675-A2 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 1997-01-22 | — | — | EP | disclosed |