Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631876 | 0.79 | KDM1A (0.41) | PDK2PDK4HTR2CSUV39H1EHMT2 | |
| SCHEMBL27473432 | 0.79 | BRD4 (0.40) | BRD4CREBBPEP300PDK2PDK4 | |
| SCHEMBL28145059 | 0.75 | PDK2 (0.37) | BRD4CREBBPEP300PDK2PDK4 | |
| SCHEMBL11378799 | 0.73 | CREBBP (0.49) | BRD4CREBBPEP300BRPF1RAB9A | |
| SCHEMBL12465642 | 0.72 | CREBBP (0.38) | BRD4CREBBPEP300PDK2PDK4 | |
| SCHEMBL4961191 | 0.72 | HTR2A (0.36) | RAB9AKDM1AALDH1A1HTR5A | |
| SCHEMBL6770129 | 0.71 | PGR (0.61) | — | |
| SCHEMBL1316216 | 0.69 | PDK2 (0.41) | BRD4CREBBPEP300PDK2PDK4 | |
| SCHEMBL12629401 | 0.69 | PDK2 (0.41) | BRD4CREBBPEP300PDK2PDK4 | |
| Iodide SCHEMBL7543439 | 0.68 | PDK2 (0.39) | BRD4CREBBPEP300PDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667562-B1 | Charge injection barrier for positive charging organic photoconductor | HEWLETT PACKARD CO (US) | 2001-03-21 | — | — | EP | claimed |
| US-20200283439-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-09-10 | — | — | US | disclosed |
| US-20190071443-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | AbbVie Deutschland GmbH & Co. KG (DE) | 2019-03-07 | — | — | US | disclosed |
| US-10118926-B2 | Tricyclic quinoline and quinoxaline derivatives | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-11-06 | — | — | US | disclosed |
| EP-2895485-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014041131-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-03-20 | — | — | WO | disclosed |
| US-20140080816-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-03-20 | — | — | US | disclosed |
| US-5644023-A | CATALYTIC POLYMERIZATION OF OLEFINS WITH CARBON MONOXIDE, REACTING A TRANSITION METAL ADSORBED ON A SUPPORT WITH AN OXIDANT AND LIGATING THE SUPPORT AND REOXIDATION INTO POSITIVE VALENCE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0698641-A1 | Cationic 1,3,4-thiadiazole dyes | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0285782-B1 | DRY TONERS CONTAINING METHINE FANAL PIGMENTS | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |
| US-4849306-A | Dry toners containing methinefanal pigments | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-18 | — | — | US | disclosed |
| EP-0285782-A1 | Dry toners containing methine fanal pigments | BAYER AG (DE) | 1988-10-12 | — | — | EP | disclosed |
| US-4144178-A | HEAT RESISTANCE | KAO SOAP CO., LTD. (JP) | 1979-03-13 | — | — | US | disclosed |
| US-3997597-A | ANTIOXIDANTS FOR LUBRICANTS AND GREASES | MOBIL OIL CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080816-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | HTR2C, HTR2A, HTR5A | BRD4 624/4885CREBBP 3991/4885EP300 2835/4885 |
| US-20200283439-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | HTR2C, HTR2A, HTR5A | BRD4 624/4885CREBBP 3991/4885EP300 2835/4885 |
| US-10118926-B2 | Tricyclic quinoline and quinoxaline derivatives | HTR2C, HTR2A, HTR5A | BRD4 624/4885CREBBP 3991/4885EP300 2835/4885 |
| US-20190071443-A1 | TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES | HTR2C, HTR2A, HTR5A | BRD4 624/4885CREBBP 3991/4885EP300 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.