SCHEMBL7759535

SCHEMBL7759535

Cc1c(Cl)nc(Cl)c(Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.39
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21241477 0.80 PDE10A (0.36) PDE10ALMNA
SCHEMBL468366 0.75 ALDH1A1 (0.36) LMNA
SCHEMBL9328700 0.73 PDE10A (0.37) PDE10ALMNA
Potassium SCHEMBL8421932 0.72 ALDH1A1 (0.33)
SCHEMBL9647771 0.72 ALDH1A1 (0.33)
Ammonia Solution, Strong SCHEMBL9646819 0.72 ALDH1A1 (0.43)
Hydrochloric Acid SCHEMBL27691899 0.72 ALDH1A1 (0.33)
SCHEMBL10652824 0.71
SCHEMBL10758318 0.71 PDE10A (0.32) PDE10A
SCHEMBL7157400 0.69 LMNA (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0063872-B1 PROCESS FOR THE PREPARATION OF FLUOROMETHYL PYRIDINES AND CERTAIN NOVEL PRODUCTS OBTAINED THEREFROM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-17 EP claimed
WO-2019149260-A1 PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2019-08-08 WO disclosed
CN-104513197-A 2-aminonicotinic acid synthetic method NANJING RED SUN CO LTD 2015-04-15 CN disclosed
CN-100348319-C Catalyst for gas-solid phase synthesis of 2-chloro-5-trichloro methyl pyridine and its prepn UNIV SOUTHEAST (CN) 2007-11-14 CN disclosed
CN-1772380-A Catalyst for gas-solid phase synthesis of 2-chloro-5-trichloro methyl pyridine and its prepn UNIV SOUTHEAST (CN) 2006-05-17 CN disclosed
EP-0791583-B1 PROCESS FOR PRODUCING 3-(AMINOMETHYL)-6-CHLOROPYRIDINES NIPPON SODA CO (JP) 2001-04-18 EP disclosed
EP-0107866-B1 TRIHALOMETHYLPYRIDINE COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-30 EP disclosed
EP-0183228-A2 Chlorine exchange for fluorine in 2-fluoro-pyridine compounds THE DOW CHEMICAL COMPANY (US) 1986-06-04 EP disclosed
EP-0162464-A1 Synthesis of 2-substituted-5-methylpyridines from methylcyclo-butanecarbonitrile, valeronitrile and pentenonitrile intermediates ICI AMERICAS INC. (US) 1985-11-27 EP disclosed
EP-0004414-B1 MIXTURES OF HERBICIDAL PYRIDYLOXYPHENOXYPROPANOIC ACID DERIVATIVES WITH OTHER HERBICIDES, AND PROCESSES OF KILLING UNWANTED PLANTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-24 EP disclosed
EP-0063872-B1 PROCESS FOR THE PREPARATION OF FLUOROMETHYL PYRIDINES AND CERTAIN NOVEL PRODUCTS OBTAINED THEREFROM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-17 EP disclosed
EP-0121320-A1 Preparation of 2-chloro-5-methylpyridine IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-10-10 EP disclosed
EP-0009212-B1 PROCESS FOR PRODUCING 2-CHLORO-5-TRICHLOROMETHYLPYRIDINE ISHIHARA SANGYO KAISHA LTD. (JP) 1984-02-08 EP disclosed
EP-0063872-A1 Process for the preparation of fluoromethyl pyridines and certain novel products obtained therefrom IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-11-03 EP disclosed
EP-0060462-A1 Preparation of 2,3-dichloro-5-trichloromethylpyridine THE DOW CHEMICAL COMPANY (US) 1982-09-22 EP disclosed
EP-0013474-A2 Preparation of 2-chloro-5-trifluoromethylpyridine IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-07-23 EP disclosed
EP-0009212-A1 Process for producing 2-chloro-5-trichloromethylpyridine ISHIHARA SANGYO KAISHA LTD. (JP) 1980-04-02 EP disclosed