Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759592 | 0.86 | CYP2C9 (0.36) | MAPTACHENPC1RAB9ASLC6A2 | |
| SCHEMBL7757153 | 0.77 | DRD2 (0.35) | NPC1RAB9AMAOBMAOAKDM1A | |
| SCHEMBL7757549 | 0.74 | SPHK1 (0.33) | NPC1RAB9AMAOBMAOA | |
| SCHEMBL7759932 | 0.73 | CYP2C9 (0.32) | MAPTSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8977220 | 0.70 | PTGS2 (0.38) | NPC1RAB9AMAOBKDM1APTGS1 | |
| SCHEMBL8021390 | 0.69 | ACHE (0.35) | ACHENPC1MEN1KMT2ATDP1 | |
| SCHEMBL17105813 | 0.69 | ACHE (0.35) | ACHETDP1 | |
| SCHEMBL8027799 | 0.68 | SPHK1 (0.37) | — | |
| SCHEMBL8042710 | 0.68 | ESR2 (0.41) | MAPTNPC1RAB9AKDM1ARCOR1 | |
| SCHEMBL8448439 | 0.68 | ESR2 (0.41) | MAPTNPC1RAB9AKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| US-5641431-A | Silacyclohexanone compound and a method of preparing a silacyclohexane-type liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |