Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | USP5 | P45974 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417019 | 0.85 | CYP2C9 (0.43) | CYP2C9CYP2D6HIF1APTPN5TYR | |
| SCHEMBL6273180 | 0.79 | TSHR (0.42) | CYP2C9CYP2D6HIF1ATYRALDH1A1 | |
| SCHEMBL167876 | 0.78 | TSHR (0.46) | ALDH1A1NPC1RAB9A | |
| SCHEMBL2068288 | 0.75 | MAPK1 (0.39) | HIF1AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7190617 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4E | |
| SCHEMBL4842726 | 0.73 | PYCR1 (0.39) | CYP2C9CYP2D6HIF1ATYRACE | |
| SCHEMBL19057995 | 0.70 | CYP2C9 (0.47) | CYP2C9CYP2D6HIF1APTPN5TYR | |
| SCHEMBL548066 | 0.69 | TSHR (0.50) | CYP2C9CYP2D6HIF1APTPN5TYR | |
| SCHEMBL6281512 | 0.69 | CYP2C9 (0.50) | CYP2C9CYP2D6HIF1APTPN5TYR | |
| SCHEMBL16191360 | 0.69 | CYP2C9 (0.50) | CYP2C9CYP2D6HIF1APTPN5TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818488-B1 | Acylsuccinic acid polyesters, process for their preparation and their utilization for duromers and coatings | BAYER AG (DE) | 2001-03-21 | — | — | EP | disclosed |
| US-5929197-A | Acylsuccinic acid polyesters, a process for their preparation and their use in thermosetting plastics and coatings | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-27 | — | — | US | disclosed |
| EP-0818488-A1 | Acylsuccinic acid polyesters, process for their preparation and their utilization for duromers and coatings | BAYER AG (DE) | 1998-01-14 | — | — | EP | disclosed |