Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 11/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 8/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL1863461 | 1.00 | SLC7A5 (0.58) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL27689301 | 0.97 | SLC7A5 (0.55) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL28948522 | 0.97 | SLC7A5 (0.62) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL692565 | 0.97 | SLC7A5 (0.62) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL138874 | 0.97 | SLC7A5 (0.62) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL2408752 | 0.97 | SLC7A5 (0.62) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL26598008 | 0.95 | SLC7A5 (0.64) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL2551557 | 0.95 | SLC7A5 (0.64) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL9721406 | 0.95 | SLC7A5 (0.64) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL1162683 | 0.94 | SLC7A5 (0.51) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097173-A1 | PEPTIDES OF IL-2 AND DERIVATIVES THEREOF AND THEIR USE AS THERAPEUTIC AGENTS | INSTITUT PASTEUR (FR) | 2001-05-09 | — | — | EP | disclosed |
| EP-0804559-A4 | ENZYME FOR CLEAVAGE OF THE ANCHOR REGION OF SURFACE PROTEINS FROM GRAM POSITIVE BACTERIA | UNIV ROCKEFELLER (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-2000004048-A1 | PEPTIDES OF IL-2 AND DERIVATIVES THEREOF AND THEIR USE AS THERAPEUTIC AGENTS | INSTITUT PASTEUR (FR) | 2000-01-27 | — | — | WO | disclosed |
| EP-0804559-A1 | ENZYME FOR CLEAVAGE OF THE ANCHOR REGION OF SURFACE PROTEINS FROM GRAM POSITIVE BACTERIA | ROCKEFELLER UNIVERSITY (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996011263-A1 | ENZYME FOR CLEAVAGE OF THE ANCHOR REGION OF SURFACE PROTEINS FROM GRAM POSITIVE BACTERIA | ROCKEFELLER UNIVERSITY (US) | 1996-04-18 | — | — | WO | disclosed |