Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77521 | 1.00 | PRKCA (0.59) | PRKCATDP1PRKCEPRKCQPRKCD | |
| SCHEMBL7758874 | 1.00 | PRKCA (0.59) | PRKCATDP1PRKCEPRKCQPRKCD | |
| Triacetin SCHEMBL22160048 | 0.98 | PRKCA (0.57) | PRKCATDP1PRKCEPRKCQPRKCD | |
| Acetic Acid SCHEMBL8675242 | 0.96 | PRKCA (0.56) | PRKCATDP1PRKCEPRKCQPRKCD | |
| Ethylene Glycol SCHEMBL16612582 | 0.96 | PRKCA (0.56) | PRKCATDP1PRKCEPRKCQPRKCD | |
| Isopropyl Alcohol SCHEMBL11286605 | 0.94 | PRKCA (0.54) | PRKCATDP1 | |
| SCHEMBL17707870 | 0.92 | PRKCA (0.53) | PRKCATDP1PRKCEPRKCQPRKCD | |
| Propylene Glycol SCHEMBL20138436 | 0.92 | PRKCA (0.53) | PRKCATDP1 | |
| Glycerin SCHEMBL4461415 | 0.92 | PRKCA (0.53) | PRKCATDP1PRKCEPRKCQPRKCD | |
| Triacetin SCHEMBL9802800 | 0.92 | PRKCA (0.57) | PRKCATDP1PRKCEPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639586-B1 | Phosphonic acid derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |
| US-5608045-A | DISODIUM SALT BY POT REACTING RHAMNOSE TRIACETATE WITH PHENYL DICHLOROPHOSPHATE IN PRESENCE OF TRIETHYLAMINE AND WITH /S/LEU-/S/TRP-OET IN SOLVENT, SAPONIFYING SEPARATED PRODUCT WITH ETHANOLIC BASE IN COLD, EVAPORATING ETHANOL | ADIR ET COMPAGNIE (FR) | 1997-03-04 | — | — | US | disclosed |
| US-5591728-A | ENZYME INHIBITORS WITH AMIDE AND ESTER GROUPS | ADIR ET COMPAGNIE (FR) | 1997-01-07 | — | — | US | disclosed |
| US-5481030-A | USED AS AN ENDOTHELIN CONVERTASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0639586-A1 | Phosphonic acid derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1995-02-22 | — | — | EP | disclosed |