Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL11286605 | 0.94 | PRKCA (0.54) | PRKCATDP1 | |
| Triacetin SCHEMBL890839 | 0.94 | PRKCA (0.46) | PRKCATDP1 | |
| SCHEMBL7758874 | 0.92 | PRKCA (0.59) | PRKCATDP1 | |
| SCHEMBL77521 | 0.92 | PRKCA (0.59) | PRKCATDP1 | |
| SCHEMBL7759898 | 0.92 | PRKCA (0.59) | PRKCATDP1 | |
| Triacetin SCHEMBL22160048 | 0.90 | PRKCA (0.57) | PRKCATDP1 | |
| Triacetin SCHEMBL15094105 | 0.89 | PRKCA (0.43) | PRKCATDP1 | |
| Glycerin SCHEMBL4461415 | 0.89 | PRKCA (0.53) | PRKCATDP1 | |
| SCHEMBL17707870 | 0.89 | PRKCA (0.53) | PRKCATDP1 | |
| Acetic Acid SCHEMBL8675242 | 0.88 | PRKCA (0.56) | PRKCATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023402-B2 | Oral care compositions | COLGATE-PALMOLIVE COMPANY (US) | 2024-07-02 | — | — | US | disclosed |
| EP-3534869-B1 | ORAL CARE COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-110150279-B | Preparation method for instant and rapid generation of peroxyacetic acid disinfectant | 南通思锐生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| EP-3532021-B1 | ANHYDROUS ORAL CARE COMPOSITION | COLGATE PALMOLIVE CO (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-115105421-A | Oral care compositions | 高露洁-棕榄公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-109982682-B | Oral care compositions | 高露洁-棕榄公司 | 2022-07-01 | — | — | CN | disclosed |
| US-20220142880-A1 | Oral Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2022-05-12 | — | — | US | disclosed |
| US-11090241-B2 | Oral care compositions | COLGATE-PALMOLIVE COMPANY (US) | 2021-08-17 | — | — | US | disclosed |
| US-11090243-B2 | Oral care composition | COLGATE-PALMOLIVE COMPANY (US) | 2021-08-17 | — | — | US | disclosed |
| US-10716742-B2 | Oral care composition | COLGATE-PALMOLIVE COMPANY (US) | 2020-07-21 | — | — | US | disclosed |
| EP-3534869-A1 | ORAL CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3532021-A1 | Oral Care Composition | Colgate-Palmolive Company (US) | 2019-09-04 | — | — | EP | disclosed |
| WO-2018118506-A1 | ORAL CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018118496-A1 | ORAL CARE COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018118498-A1 | ORAL CARE COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2018-06-28 | — | — | WO | disclosed |
| US-20180168969-A1 | Oral Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2018-06-21 | — | — | US | disclosed |
| US-20180168972-A1 | Oral Care Composition | COLGATE-PALMOLIVE COMPANY (US) | 2018-06-21 | — | — | US | disclosed |
| US-20180168993-A1 | Oral Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2018-06-21 | — | — | US | disclosed |
| WO-2018093357-A1 | Oral Care Composition | COLGATE-PALMOLIVE COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |
| US-20180133130-A1 | Oral Care Composition | COLGATE-PALMOLIVE COMPANY (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12023402-B2 | Oral care compositions | VKORC1L1, PRDX1, VKORC1 | PRKCA 3842/4885TDP1 2259/4885 |
| US-20180133130-A1 | Oral Care Composition | PRDX1, PRDX2, PRDX4 | PRKCA 4008/4885TDP1 1670/4885 |
| US-20180168993-A1 | Oral Care Compositions | VKORC1L1, PRDX1, VKORC1 | PRKCA 3842/4885TDP1 2259/4885 |
| US-20220142880-A1 | Oral Care Compositions | VKORC1L1, PRDX1, VKORC1 | PRKCA 3842/4885TDP1 2259/4885 |
| US-11090243-B2 | Oral care composition | NONO, COG7, DSG1 | PRKCA 4026/4885TDP1 2268/4885 |
| US-20180168969-A1 | Oral Care Compositions | NONO, DSG1, SCD5 | PRKCA 3772/4885TDP1 2669/4885 |
| US-10716742-B2 | Oral care composition | PRDX1, PRDX2, PRDX4 | PRKCA 4008/4885TDP1 1670/4885 |
| US-11090241-B2 | Oral care compositions | NONO, DSG1, SCD5 | PRKCA 3772/4885TDP1 2669/4885 |
| US-20180168972-A1 | Oral Care Composition | NONO, COG7, DSG1 | PRKCA 4026/4885TDP1 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.