SCHEMBL7759906

SCHEMBL7759906

NCCNCCCC1CCCOC1[SiH3]

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.34
CA6 P23280 3/20 0.34
CA7 P43166 3/20 0.34
CA9 Q16790 3/20 0.34
CA14 Q9ULX7 3/20 0.34
CA5B Q9Y2D0 3/20 0.34
CA2 P00918 2/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA5A P35218 2/20 0.34
MEN1 O00255 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
CA1 P00915 1/20 0.31
ALOX15 P16050 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1309550 0.77 CA12 (0.35) CA12CA6CA7CA9CA14
SCHEMBL3716185 0.67
SCHEMBL22899653 0.67 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL4400012 0.67 ACACB (0.31)
SCHEMBL6965163 0.65 SIGMAR1 (0.56) CA12CA6CA7CA9CA14
SCHEMBL8111404 0.65 ANPEP (0.49) KMT2ALMNAALDH1A1TP53KDM4E
SCHEMBL10064353 0.65 ANPEP (0.49) KMT2ALMNAALDH1A1TP53KDM4E
SCHEMBL6968473 0.64 CA12 (0.52) CA12CA6CA7CA9CA14
SCHEMBL23131807 0.64 SIGMAR1 (0.59) CA12CA6CA7CA9CA14
SCHEMBL21173520 0.64 SIGMAR1 (0.59) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714961-B1 Composition for coating rubber or latex articles KENDALL PROCLINICS S L (ES) 2001-04-11 EP disclosed