SCHEMBL8111404

SCHEMBL8111404

NCCNCC1CCCO1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.49
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KMT2A Q03164 3/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 2/20 0.46
TP53 P04637 1/20 0.46
ALOX12 P18054 1/20 0.46
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064353 1.00 ANPEP (0.49) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL10151332 0.92 ANPEP (0.46) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL15671149 0.88 USP2 (0.50) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL22876904 0.87 ANPEP (0.42) ANPEPUSP2SMN1; SMN2KMT2APKM
Bromide SCHEMBL15671179 0.86 KMT2A (0.50) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL611743 0.83 KMT2A (0.53) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL15740339 0.81 USP2 (0.45) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL12846940 0.81 USP2 (0.45) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL11413505 0.81 KMT2A (0.46) ANPEPUSP2SMN1; SMN2KMT2APKM
SCHEMBL3428839 0.81 USP2 (0.49) ANPEPUSP2SMN1; SMN2KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382411-A1 ADHESIVE FOR BONDING MEMBRANES MADE OF SOFT PVC SIKA TECHNOLOGY AG (CH) 2025-12-18 US claimed
EP-4377372-A1 AMINE HARDENER WITH HIGH CONTENT IN RENEWABLE CARBON Sika Technology AG (CH) 2024-06-05 EP claimed
CN-117460757-A Amine curing agent with high renewable carbon content SIKA技术股份公司 2024-01-26 CN claimed
WO-2023006598-A1 AMINE HARDENER WITH HIGH CONTENT IN RENEWABLE CARBON SIKA TECHNOLOGY AG (CH) 2023-02-02 WO claimed
US-20260078214-A1 CURING AGENT FOR EPOXY RESINS, WHICH CURING AGENT HAS DIPHENOLIC ACID SIKA TECHNOLOGY AG (CH) 2026-03-19 US disclosed
US-20250382411-A1 ADHESIVE FOR BONDING MEMBRANES MADE OF SOFT PVC SIKA TECHNOLOGY AG (CH) 2025-12-18 US disclosed
WO-2025233393-A1 EPOXY RESIN COATING WITH BIO-BASED GRANULATE ADMIXED DURING USE SIKA TECHNOLOGY AG (CH) 2025-11-13 WO disclosed
WO-2025233246-A1 FLOOR PROTECTION SYSTEM SCATTERED WITH BIO-BASED GRANULAR MATERIAL SIKA TECHNOLOGY AG (CH) 2025-11-13 WO disclosed
US-20250326885-A1 SOLUTION OF POLYPHENOLS IN AMINE SIKA TECHNOLOGY AG (CH) 2025-10-23 US disclosed
EP-4565659-A1 EPOXY RESIN COMPOSITION WITH BIO-BASED GRANULAR MATERIAL Sika Technology AG (CH) 2025-06-11 EP disclosed
EP-4377372-B1 AMINE CURING AGENT WITH HIGH RECOVERABLE CARBON CONTENT SIKA TECH AG (CH) 2025-05-07 EP disclosed
EP-4543959-A1 SOLUTION OF POLYPHENOLS IN AMINE Sika Technology AG (CH) 2025-04-30 EP disclosed
US-20100160309-A1 INHIBITORS OF JANUS KINASES AND/OR 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 MERCK SHARP & DOHME LLC 2010-06-24 US disclosed
WO-2010053572-A2 AMINOALCOHOL LIPIDOIDS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-05-14 WO disclosed
EP-0685477-B1 Insecticidal tetrahydrofuran-compound MITSUI CHEMICALS INC (JP) 2000-10-18 EP disclosed
US-5614527-A NITROGUANIDINE COMPOUND MITSUI TOATSU CHEMICALS, INC. (JP) 1997-03-25 US disclosed
EP-0685477-A1 Insecticidal tetrahydrofuran-compound MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-12-06 EP disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed
US-4230856-A 1,2,3,4-Tetrahydropyrrolo-[1,2-a]-pyrazine SKOLDINOV ALEXANDR P 1980-10-28 US disclosed
US-4216321-A 3,4-Dihydropyrrolo-[1,2-a]-pyrazine and method of preparing same NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII (SU) 1980-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160309-A1 INHIBITORS OF JANUS KINASES AND/OR 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 JAK2, PDK1, JAK1 ANPEP 2892/4885USP2 2330/4885SMN1; SMN2 4087/4885
US-20260078214-A1 CURING AGENT FOR EPOXY RESINS, WHICH CURING AGENT HAS DIPHENOLIC ACID PTGER1, DDAH1, MEP1A ANPEP 2012/4885USP2 955/4885SMN1; SMN2 2293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.