Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118019 | 0.96 | TSHR (0.64) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20312877 | 0.95 | TSHR (0.68) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8850905 | 0.94 | TSHR (0.67) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8850957 | 0.94 | TSHR (0.67) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8850656 | 0.94 | TSHR (0.67) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8850371 | 0.94 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5685352 | 0.94 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4945997 | 0.94 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11439251 | 0.94 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10390293 | 0.94 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295617-B2 | Dental composition, method of producing and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-29 | — | — | US | disclosed |
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| EP-0795580-B1 | VULCANIZABLE RUBBER COMPOSITION, SEAL TO BE USED IN DYNAMIC STATE, AND MATERIAL THEREFOR | NIPPON ZEON CO (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5852093-A | Vulcanizable rubber composition, seal used in dynamic state, and sealing material | NIPPON ZEON CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0704480-B1 | Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber | NIPPON ZEON CO (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5683819-A | Composite of highly saturated nitrile rubber with fiber, and belt composed thereof | NIPPON ZEON CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0704479-B1 | Composite of highly saturated nitrile rubber with fiber, and belt composed thereof | NIPPON ZEON CO (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0704459-B1 | Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition | NIPPON ZEON CO (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0795580-A1 | VULCANIZABLE RUBBER COMPOSITION, SEAL TO BE USED IN DYNAMIC STATE, AND MATERIAL THEREFOR | NIPPON ZEON CO., LTD. (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5651995-A | Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition | NIPPON ZEON CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5556919-A | Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber | NIPPON ZEON CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0704459-A1 | Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition | NIPPON ZEON CO., LTD. (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704480-A1 | Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber | NIPPON ZEON CO., LTD. (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704479-A1 | Composite of highly saturated nitrile rubber with fiber, and belt composed thereof | NIPPON ZEON CO., LTD. (JP) | 1996-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | PAM, PTMS, ACR | TSHR 3551/4885ALDH1A1 2692/4885TP53 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.