Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | PPIA | P62937 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | FPR2 | P25090 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810510 | 0.88 | PPIA (0.76) | NPC1SMN1; SMN2MAPTPPIABRD4 | |
| SCHEMBL8366817 | 0.84 | BRD4 (0.59) | NPC1RAB9ASMN1; SMN2MAPTBRD4 | |
| SCHEMBL7756903 | 0.82 | BRD4 (0.53) | NPC1RAB9ASMN1; SMN2MAPTBRD4 | |
| SCHEMBL3150397 | 0.81 | P2RY1 (0.62) | NPC1RAB9ASMN1; SMN2MAPTPPIA | |
| SCHEMBL7756925 | 0.80 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTBRD4 | |
| SCHEMBL3163849 | 0.80 | PPIA (0.64) | PPIABRD4FPR2 | |
| SCHEMBL7760885 | 0.80 | HIF1A (0.78) | NPC1RAB9ASMN1; SMN2MAPTHIF1A | |
| SCHEMBL11106394 | 0.78 | RAB9A (0.85) | NPC1RAB9ASMN1; SMN2MAPTHIF1A | |
| SCHEMBL5152592 | 0.77 | BRD4 (0.57) | NPC1RAB9APPIABRD4CASP3 | |
| SCHEMBL3147715 | 0.77 | P2RY1 (0.63) | PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |