Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756925 | 0.86 | NPC1 (0.49) | BRD4HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL8366817 | 0.84 | BRD4 (0.59) | BRD4HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL7760029 | 0.82 | NPC1 (0.67) | BRD4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7756878 | 0.81 | KDM4E (0.58) | HDAC1HDAC3HDAC2NCOR2NPC1 | |
| SCHEMBL7760871 | 0.81 | PLA2G1B (0.57) | BRD4NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL7760879 | 0.78 | MAPT (0.53) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6771484 | 0.74 | HDAC3 (0.55) | BRD4HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3585982 | 0.74 | HDAC8 (0.55) | BRD4HDAC1HDAC3HDAC2RAB9A | |
| SCHEMBL13366908 | 0.73 | CASR (0.63) | HDAC1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL321103 | 0.73 | LTA4H (0.68) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |