Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329097 | 0.81 | NUDT1 (0.55) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL18285289 | 0.81 | ADORA2A (0.59) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL638259 | 0.81 | ADORA2A (0.55) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL20035085 | 0.79 | ADORA2A (0.51) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL8070078 | 0.78 | MEN1 (0.65) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL30725589 | 0.77 | ADORA2A (0.50) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL26314584 | 0.77 | ADORA2A (0.50) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL13584749 | 0.77 | ADORA2A (0.50) | ADORA2ANUDT1MAPTMEN1KMT2A | |
| SCHEMBL17194216 | 0.76 | GPR3 (0.53) | NUDT1MAPTMEN1KMT2AGAA | |
| SCHEMBL26214818 | 0.75 | NUDT1 (0.47) | ADORA2ANUDT1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087790-A2 | USE OF A COMPOUND HAVING AFFINITY FOR THE BENZODIAZEPINE MITOCHONDRIAL RECEPTOR IN CANCER THERAPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999066958-A2 | USE OF A COMPOUND HAVING AFFINITY FOR THE BENZODIAZEPINE MITOCHONDRIAL RECEPTOR IN CANCER THERAPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1999-12-29 | — | — | WO | disclosed |
| EP-0210084-B1 | AMIDES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0210084-A1 | Amides, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1987-01-28 | — | — | EP | disclosed |