SCHEMBL7760190

SCHEMBL7760190

C=C(C)C(=O)OC(C)CN1C(=O)C2CCC(C)CC2C1=O

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.35
ALDH1A1 P00352 5/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PKM P14618 1/20 0.34
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
KMT2A Q03164 3/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
MEN1 O00255 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760745 0.83 STAT3 (0.35) STAT3ALDH1A1GAASMN1; SMN2PKM
SCHEMBL8011685 0.75 STAT3 (0.40) STAT3ALDH1A1GAASMN1; SMN2PKM
SCHEMBL17532414 0.72 LMNA (0.39) STAT3ALDH1A1GAASMN1; SMN2PKM
SCHEMBL17532485 0.70 HTT (0.40) ALDH1A1SMN1; SMN2LMNARAB9AL3MBTL1
SCHEMBL10335783 0.69 LMNA (0.43) STAT3ALDH1A1GAASMN1; SMN2PKM
SCHEMBL149716 0.68 TSHR (0.40) ALDH1A1KMT2A
SCHEMBL17532488 0.67 HTT (0.43) ALDH1A1SMN1; SMN2LMNARAB9AKMT2A
SCHEMBL17532472 0.67 POLB (0.49) STAT3ALDH1A1LMNAPOLBKMT2A
SCHEMBL12098030 0.66 SMN1; SMN2 (0.36) ALDH1A1SMN1; SMN2LMNARAB9APOLB
SCHEMBL18485395 0.66 STAT3 (0.43) STAT3ALDH1A1GAASMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1090775-A1 Image recording sheet comprising an active energy ray-curable composition OJI PAPER COMPANY LIMITED (JP) 2001-04-11 EP claimed
EP-1090775-A1 Image recording sheet comprising an active energy ray-curable composition OJI PAPER COMPANY LIMITED (JP) 2001-04-11 EP disclosed