SCHEMBL7760299

SCHEMBL7760299

CCNc1ccc(O)c(I)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.43
ARG1 P05089 1/20 0.40
ADRA2A P08913 3/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
NR1H4 Q96RI1 1/20 0.38
ESR1 P03372 1/20 0.38
RECQL P46063 2/20 0.36
MAPT P10636 2/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 2/20 0.35
EGFR P00533 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29642426 0.81 ARG1 (0.59) IDO1ARG1ADRA2AADRA2BADRA2C
SCHEMBL347616 0.81 ARG1 (0.59) IDO1ARG1ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL1825913 0.79 ARG1 (0.57) IDO1ARG1ADRA2AADRA2BADRA2C
SCHEMBL6572164 0.78 ESR1 (0.48) IDO1ARG1ESR1RECQLMAPT
SCHEMBL27479818 0.77 ALDH1A1 (0.39) IDO1ADRA2AADRA2BADRA2CNR1H4
SCHEMBL14279552 0.76 NR1H4 (0.51) IDO1ARG1ADRA2AADRA2BADRA2C
SCHEMBL10801815 0.76 IDO1 (0.43) IDO1ARG1ADRA2AADRA2BADRA2C
SCHEMBL3395942 0.76 POLB (0.45) ADRA2AADRA2BADRA2CNR1H4RECQL
SCHEMBL9860649 0.76 MAPT (0.40) ADRA2AADRA2BADRA2CRECQLMAPT
Hydrochloric Acid SCHEMBL3398573 0.74 POLB (0.44) ADRA2AADRA2BADRA2CNR1H4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595743-B1 Bihaptinic derivatives for binding technetium or rhenium, process for their preparation, application for diagnosis and therapy, kits and immunological reactants comprising them. IMMUNOTECH PARTNERS (FR) 2001-03-14 EP disclosed
EP-0595743-A1 Bihaptinic derivatives for binding for technetium or rhenium, process for their preparation, application for diagnosis and therapy, kits and immunological reactants comprising them IMMUNOTECH PARTNERS:Société Anonyme dite (FR) 1994-05-04 EP disclosed