SCHEMBL7760596

SCHEMBL7760596

CCCCO[Si](C)(CCCCl)OCCCC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.39
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP19A1 P11511 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11369852 0.94 TSHR (0.37) TSHRTDP1ALDH1A1
SCHEMBL600889 0.89 TSHR (0.38) TSHRTDP1ALDH1A1
SCHEMBL706695 0.86 ADRB2 (0.38) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL705364 0.86 ADRB2 (0.38) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL28805966 0.86 ADRB2 (0.38) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL7760477 0.85
SCHEMBL703594 0.84 ADRB2 (0.39) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL29201552 0.83 TSHR (0.39) TSHRTDP1ALDH1A1
SCHEMBL17937858 0.83 TSHR (0.42) TSHRTDP1ALDH1A1ADRB2ADRB1
SCHEMBL11332073 0.82 THRB (0.38) TSHRTDP1ALDH1A1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924347-A Preparation method of monosulfur organosilane coupling agent 江西宏柏新材料股份有限公司 2024-04-26 CN claimed
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US claimed
CN-118580266-A Sulfur silane coupling agent containing polysulfide and continuous preparation method thereof 江西宏柏新材料股份有限公司 2024-09-03 CN disclosed
CN-117924347-A Preparation method of monosulfur organosilane coupling agent 江西宏柏新材料股份有限公司 2024-04-26 CN disclosed
EP-3260515-A1 POLISHING COMPOSITION Fujimi Incorporated (JP) 2017-12-27 EP disclosed
US-20160288289-A1 POLISHING COMPOSITION FUJIMI INCORPORATED (JP) 2016-10-06 US disclosed
EP-3048152-A1 POLISHING COMPOSITION Fujimi Incorporated (JP) 2016-07-27 EP disclosed
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed
US-6277902-B1 RUBBER COMPOUNDS COMPRISING SOLUBLE RUBBER, HYDROPHOBIZED FILLER HAVING SPECIFIED METHANOL WETTABILITY, SUPPORTEDPOLYSULFIDIC-SILANE COMPOUNDS PREPARED BY REACTION OF HALOALKYLSILANES, ORGANIC HALOGEN COMPOUNDS AND POLYSULFIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
EP-0705838-B1 Process for the preparation of silane polysulfides CROMPTON CORP (US) 2001-05-23 EP disclosed
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US disclosed
US-5770754-A Method of preparing polysulphidic silyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1998-06-23 US disclosed
US-5596116-A Process for the preparation of silane polysulfides OSI SPECIALTIES, INC. (US) 1997-01-21 US disclosed
EP-0705838-A2 Process for the preparation of silane polysulfides OSi SPECIALTIES, INC. (US) 1996-04-10 EP disclosed
US-5489701-A REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION OSI SPECIALTIES, INC. (US) 1996-02-06 US disclosed
US-5466848-A Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane OSI SPECIALTIES, INC. (US) 1995-11-14 US disclosed
US-5399739-A Method of making sulfur-containing organosilanes WRIGHT CHEMICAL CORPORATION (US) 1995-03-21 US disclosed
US-4129585-A NO FORMATION OF HYDROGEN SULFIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-12-12 US disclosed