Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166025 | 0.96 | MAPT (0.53) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL7756156 | 0.90 | HDAC6 (0.49) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL7760514 | 0.87 | CHEK2 (0.56) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL7759421 | 0.87 | HDAC6 (0.55) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL9166033 | 0.85 | MAPT (0.53) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL7759314 | 0.84 | HDAC6 (0.66) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL7761115 | 0.83 | MAPT (0.49) | HDAC6MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6576423 | 0.81 | CYP1A2 (0.45) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| Ensulizole SCHEMBL29405567 | 0.79 | HDAC6 (0.79) | HDAC6MAPTTP53SMN1; SMN2KDM4E | |
| Ensulizole SCHEMBL16277 | 0.79 | HDAC6 (0.79) | HDAC6MAPTTP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579827-B1 | METHOD OF PREPARING 2-ARYLBENZIMIDAZOLE 5-SULPHONIC ACIDS | MERCK PATENT GMBH (DE) | 2001-04-18 | — | — | EP | disclosed |