Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683508 | 0.87 | OPRM1 (0.58) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL6664282 | 0.83 | OPRM1 (0.48) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL6662792 | 0.82 | OPRM1 (0.55) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL6667234 | 0.82 | OPRM1 (0.48) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL7744512 | 0.78 | OPRM1 (0.66) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL6695001 | 0.77 | OPRM1 (0.65) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| Hydrochloric Acid SCHEMBL7738855 | 0.76 | OPRM1 (0.64) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL6663547 | 0.73 | OPRM1 (0.50) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL6662830 | 0.71 | OPRM1 (0.57) | OPRM1OPRL1ADRA2ADRD4SLC6A4 | |
| SCHEMBL6694942 | 0.71 | OPRM1 (0.65) | OPRM1OPRL1ADRA2ADRD4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097924-A1 | 4-hydroxy-4-phenylpiperidine derivatives having -opioid agonist activity and pharmaceuticals containing the same | SSP Co., Ltd. (JP) | 2001-05-09 | — | — | EP | disclosed |