SCHEMBL7760744

SCHEMBL7760744

NC(=O)Nc1ccc(C2CCCCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 0.60
HDAC6 Q9UBN7 3/20 0.60
HDAC3 O15379 2/20 0.60
HDAC11 Q96DB2 2/20 0.60
DEGS1 O15121 1/20 0.60
MITF O75030 1/20 0.56
KLF5 Q13887 1/20 0.56
ALDH1A1 P00352 6/20 0.55
HPGD P15428 2/20 0.55
NPC1 O15118 3/20 0.52
USP2 O75604 2/20 0.52
PEPD P12955 1/20 0.50
HDAC1 Q13547 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
RORC P51449 1/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TP53 P04637 1/20 0.48
RAB9A P51151 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19085063 0.98 HDAC8 (0.58) HDAC8HDAC6HDAC3HDAC11DEGS1
SCHEMBL12810977 0.91 HDAC3 (0.57) HDAC8HDAC6HDAC3HDAC11DEGS1
SCHEMBL11356835 0.85 HDAC8 (0.64) HDAC8HDAC6HDAC3HDAC11DEGS1
SCHEMBL11215485 0.84 HDAC8 (0.62) HDAC8HDAC6HDAC3HDAC11DEGS1
SCHEMBL31037442 0.83 NAMPT (0.59) NAMPT
SCHEMBL8742405 0.82 HDAC8 (0.53) HDAC8HDAC6HDAC3HDAC11DEGS1
SCHEMBL3428205 0.82 HDAC3 (0.53) HDAC8HDAC6HDAC3HDAC11DEGS1
SCHEMBL3822159 0.82 SLC18A3 (0.67) HDAC8HDAC6HDAC3HDAC11DEGS1
SCHEMBL29034045 0.82 EPHX1 (0.62) RORC
SCHEMBL3543861 0.81 HDAC8 (0.56) HDAC8HDAC6HDAC3HDAC11DEGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 HDAC8 1623/4885HDAC6 2384/4885HDAC3 1926/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 HDAC8 1623/4885HDAC6 2384/4885HDAC3 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.