Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14967144 | 1.00 | TSHR (0.45) | TSHRALDH1A1GABRA1GABRB2MAPT | |
| SCHEMBL14967207 | 0.86 | TSHR (0.50) | TSHRALDH1A1LMNAHPGDTP53 | |
| SCHEMBL7772636 | 0.85 | TSHR (0.61) | TSHRALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL9488854 | 0.85 | TSHR (0.61) | TSHRALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL7770452 | 0.85 | TSHR (0.61) | TSHRALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL16303826 | 0.85 | TSHR (0.61) | TSHRALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL7776125 | 0.84 | EPHX1 (0.53) | TSHRALDH1A1HPGDTP53PTGS2 | |
| SCHEMBL8503544 | 0.83 | BACE1 (0.52) | TSHRALDH1A1GABRA1GABRB2MAPT | |
| SCHEMBL7141149 | 0.83 | BACE1 (0.52) | TSHRALDH1A1GABRA1GABRB2MAPT | |
| SCHEMBL3201276 | 0.83 | BACE1 (0.52) | TSHRALDH1A1GABRA1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860439-B1 | Process for preparing an optically active phenylglycidyl acid derivative | DSM NV (NL) | 2001-06-13 | — | — | EP | disclosed |
| US-6025506-A | Process for preparing an optically active phenylglycidyl acid derivative | DSM N.V. (NL) | 2000-02-15 | — | — | US | disclosed |
| EP-0860439-A1 | Process for preparing an optically active phenylglycidyl acid derivative | DSM N.V. (NL) | 1998-08-26 | — | — | EP | disclosed |