Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772636 | 1.00 | TSHR (0.61) | TSHREPHX1ABCB1RECQLMEN1 | |
| SCHEMBL16303826 | 1.00 | TSHR (0.61) | TSHREPHX1ABCB1RECQLMEN1 | |
| SCHEMBL9488854 | 1.00 | TSHR (0.61) | TSHREPHX1ABCB1RECQLMEN1 | |
| SCHEMBL14967207 | 0.87 | TSHR (0.50) | TSHREPHX1ABCB1RECQLMEN1 | |
| SCHEMBL7776125 | 0.85 | EPHX1 (0.53) | TSHREPHX1ABCB1RECQLMEN1 | |
| SCHEMBL14967144 | 0.85 | TSHR (0.45) | TSHRRECQLTP53HPGDALDH1A1 | |
| SCHEMBL7760857 | 0.85 | TSHR (0.45) | TSHRRECQLTP53HPGDALDH1A1 | |
| SCHEMBL4024959 | 0.82 | MAOB (0.48) | TSHRMEN1TP53CYP1A2CYP2C19 | |
| SCHEMBL7770852 | 0.82 | RIPK1 (0.43) | TSHREPHX1TP53CYP2C19KMT2A | |
| SCHEMBL7776122 | 0.82 | RIPK1 (0.43) | TSHREPHX1TP53CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821679-B1 | ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE | CHIROTECH TECHNOLOGY LTD (GB) | 2001-07-11 | — | — | EP | claimed |
| US-10301397-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2019-05-28 | — | — | US | disclosed |
| US-20160340447-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-9458270-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2016-10-04 | — | — | US | disclosed |
| EP-2780177-B1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORP (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-20140296445-A1 | Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow | BRIDGESTONE CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| EP-2780177-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | Bridgestone Corporation (JP) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013075074-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2013-05-23 | — | — | WO | disclosed |
| EP-0821679-B1 | ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE | CHIROTECH TECHNOLOGY LTD (GB) | 2001-07-11 | — | — | EP | disclosed |
| US-6228955-B1 | CATALYTIC EPOXIDATION OF A CORRESPONDING PROCHIRALM, NON-ENOLIZABLE A/B-UNSATURATED KETONE | CHIROTECH TECHNOLOGY, LTD. (GB) | 2001-05-08 | — | — | US | disclosed |
| EP-0821679-A1 | ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE | Chiroscience Limited (GB) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033183-A1 | ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE | CHIROSCIENCE LIMITED (GB) | 1996-10-24 | — | — | WO | disclosed |
| US-4924012-A | Process for preparing derivatives of baccatine III and of 10-deacetyl baccatine III | RHONE-POULENC SANTE (FR) | 1990-05-08 | — | — | US | disclosed |