Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922998 | 0.78 | CRBN (0.54) | ADRA1DADRA1AADRA1BHDAC3HPGD | |
| SCHEMBL5055189 | 0.78 | CRBN (0.54) | ADRA1DADRA1AADRA1BHDAC3HPGD | |
| SCHEMBL7760016 | 0.77 | HPGD (0.53) | HDAC3HPGDALDH1A1KDM4EHDAC1 | |
| SCHEMBL11230535 | 0.76 | HPGD (0.64) | HDAC3HPGDALDH1A1KDM4ETSHR | |
| SCHEMBL3861140 | 0.75 | TSHR (0.60) | HPGDTSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL7761935 | 0.75 | KMT2A (0.51) | HDAC3HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7756867 | 0.75 | HCRTR1 (0.56) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL8652703 | 0.73 | TSHR (0.53) | HPGDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL19347407 | 0.72 | TSHR (0.49) | HPGDALDH1A1KDM4ETSHRHTT | |
| SCHEMBL21883932 | 0.71 | TSHR (0.56) | HDAC3HPGDALDH1A1KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |