Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | CD38 | P28907 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12725545 | 0.83 | MEN1 (0.60) | HPGDHDAC1KMT2ACD38HDAC3 | |
| SCHEMBL7756878 | 0.83 | KDM4E (0.58) | HDAC1KMT2AHDAC3HDAC2NCOR2 | |
| SCHEMBL1505239 | 0.80 | ALDH1A1 (0.68) | HPGDKMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12725538 | 0.80 | HIF1A (0.53) | HPGDHDAC1KMT2ACD38KDM4E | |
| SCHEMBL1714655 | 0.80 | NPC1 (0.63) | HPGDHDAC1KMT2ACD38NCOR2 | |
| SCHEMBL9741286 | 0.78 | NPC1 (0.53) | HPGDHDAC1KMT2ACD38KDM4E | |
| SCHEMBL7760871 | 0.78 | PLA2G1B (0.57) | HPGDKMT2ATSHRKDM4ELMNA | |
| SCHEMBL28678439 | 0.78 | HIF1A (0.61) | HPGDKMT2ATSHRKDM4ELMNA | |
| SCHEMBL7761717 | 0.77 | KDM4E (0.62) | HPGDHDAC1KMT2ASLC6A5HDAC3 | |
| SCHEMBL7760875 | 0.77 | ADRA1D (0.46) | HPGDHDAC1KMT2AHDAC3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |