Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365176 | 0.79 | CTSD (0.68) | HCRTR1NPC1MEN1KMT2APOLB | |
| SCHEMBL7760871 | 0.79 | PLA2G1B (0.57) | HCRTR1SGMS2NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL9585041 | 0.77 | CTSD (0.66) | HCRTR1NPC1MEN1KMT2APOLB | |
| SCHEMBL15923372 | 0.76 | NPSR1 (0.73) | HCRTR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11230535 | 0.75 | HPGD (0.64) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL7760875 | 0.75 | ADRA1D (0.46) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL3861140 | 0.74 | TSHR (0.60) | HCRTR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7761935 | 0.74 | KMT2A (0.51) | NPC1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL19268650 | 0.73 | SGMS2 (0.58) | SGMS2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14459998 | 0.72 | HCRTR1 (0.67) | HCRTR1SGMS2MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |