Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761696 | 0.87 | PKM (0.50) | KDM4ETDP1ALDH1A1HSD17B10PKM | |
| SCHEMBL15134832 | 0.79 | KDM4E (1.00) | KDM4ETDP1ALDH1A1HSD17B10PKM | |
| SCHEMBL7756951 | 0.79 | NPSR1 (0.52) | KDM4EALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL7756944 | 0.79 | KDM4E (0.55) | KDM4ETDP1ALDH1A1HSD17B10PKM | |
| SCHEMBL7761708 | 0.76 | KDM4E (0.52) | KDM4ETDP1ALDH1A1HSD17B10PKM | |
| SCHEMBL4306314 | 0.75 | KDM4E (0.67) | KDM4ETDP1ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL28275012 | 0.73 | KDM4E (0.88) | KDM4ETDP1ALDH1A1HSD17B10PKM | |
| SCHEMBL14372224 | 0.72 | NPC1 (0.65) | KDM4ETDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL5472187 | 0.72 | KDM4E (0.63) | KDM4ETDP1ALDH1A1HSD17B10PKM | |
| SCHEMBL1574755 | 0.72 | TDP1 (0.56) | KDM4ETDP1ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |