Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760053 | 0.86 | POLB (0.50) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL7763257 | 0.82 | L3MBTL1 (0.51) | KDM4EALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7760905 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL7761708 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL4306314 | 0.78 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL14372224 | 0.75 | NPC1 (0.65) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL4299291 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL22218315 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL4299533 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10TDP1KMT2A | |
| SCHEMBL5464838 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |