SCHEMBL7760946

SCHEMBL7760946

C[Si](C)(C)C(I)CCCO

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29197345 0.69
SCHEMBL16970022 0.67
SCHEMBL16969605 0.65
SCHEMBL6622357 0.65
SCHEMBL7839351 0.63
SCHEMBL3421452 0.63
SCHEMBL25226552 0.61
SCHEMBL325283 0.61 LMNA (0.47) ALDH1A1
SCHEMBL23739 0.61
SCHEMBL7071804 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738263-B1 SUBSTITUTED PHENYLIMIDAZOLIDINES HAVING ANTIANDROGEN ACTIVITY AVENTIS PHARMA SA (FR) 2001-04-04 EP disclosed
US-5750553-A ANTIANDROGENIC AGENTS ROUSSEL UCLAF (FR) 1998-05-12 US disclosed
EP-0738263-A1 NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1996-10-23 EP disclosed
WO-1995018794-A1 NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1995-07-13 WO disclosed