Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7759239 | 0.88 | MEN1 (0.34) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7761005 | 0.88 | NOX1 (0.39) | GAAMEN1KMT2AHTTALDH1A1 | |
| Diethylamine SCHEMBL7759719 | 0.85 | MEN1 (0.35) | GAAMEN1KMT2AALDH1A1ELANE | |
| Diethylamine SCHEMBL7761090 | 0.83 | SMN1; SMN2 (0.41) | KDM4EPKMGAAMEN1KMT2A | |
| Diethylamine SCHEMBL8973650 | 0.83 | SOAT1 (0.41) | KMT2AICMTALBPOLB | |
| Diethylamine SCHEMBL7761052 | 0.81 | MEN1 (0.36) | GAAMEN1KMT2AHTTALDH1A1 | |
| Diethylamine SCHEMBL9400390 | 0.81 | KMT2A (0.41) | KDM4EGAAMEN1KMT2AHTT | |
| Diethylamine SCHEMBL7762459 | 0.81 | MEN1 (0.36) | KDM4EGAAMEN1KMT2AHTT | |
| Diethylamine SCHEMBL7762421 | 0.80 | MEN1 (0.36) | GAAMEN1KMT2AALDH1A1ELANE | |
| Diethylamine SCHEMBL7762398 | 0.79 | L3MBTL1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665462-B1 | Thermofixable photosensitive recording material and process for preparing thereof | NEW OJI PAPER CO LTD (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5565306-A | SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN | NEW OJI PAPER CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0665462-A1 | Thermofixable photosensitive recording material and process for preparing thereof | NEW OJI PAPER CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |