Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7759719 | 0.91 | MEN1 (0.35) | MEN1KMT2AALDH1A1ELANEUSP2 | |
| Diethylamine SCHEMBL7761010 | 0.88 | KDM4E (0.34) | MEN1KMT2AALDH1A1ELANEPTPN1 | |
| SCHEMBL7759232 | 0.87 | CNR2 (0.41) | MEN1KMT2AALDH1A1LMNATSHR | |
| Diethylamine SCHEMBL7761090 | 0.85 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1LMNATHRB | |
| Dimethylamine SCHEMBL7760667 | 0.84 | MEN1 (0.38) | MEN1KMT2AALDH1A1ELANEUSP2 | |
| Diethylamine SCHEMBL7762398 | 0.83 | L3MBTL1 (0.38) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| Diethylamine SCHEMBL9400390 | 0.82 | KMT2A (0.41) | MEN1KMT2AALDH1A1LMNAELANE | |
| Diethylamine SCHEMBL7761052 | 0.82 | MEN1 (0.36) | MEN1KMT2AALDH1A1ELANETSHR | |
| Diethylamine SCHEMBL7762459 | 0.82 | MEN1 (0.36) | MEN1KMT2AALDH1A1LMNAELANE | |
| Diethylamine SCHEMBL7762421 | 0.81 | MEN1 (0.36) | MEN1KMT2AALDH1A1LMNAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665462-B1 | Thermofixable photosensitive recording material and process for preparing thereof | NEW OJI PAPER CO LTD (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5565306-A | SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN | NEW OJI PAPER CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0665462-A1 | Thermofixable photosensitive recording material and process for preparing thereof | NEW OJI PAPER CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |