Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 4/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GYS1 | P13807 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15647912 | 0.82 | RXFP1 (0.47) | ENPP1KDM4EMAPTPOLBALDH1A1 | |
| SCHEMBL15648268 | 0.82 | ENPP1 (0.42) | ENPP1ESR1DHODHLMNAESR2 | |
| SCHEMBL16632042 | 0.80 | ENPP1 (0.67) | ENPP1ESR1ESR2KDM4EMAPT | |
| SCHEMBL2788828 | 0.79 | KDM4E (0.42) | LMNAKDM4EMAPTPOLBDCTPP1 | |
| SCHEMBL625364 | 0.77 | LMNA (0.46) | ESR1DHODHPDE10ALMNAESR2 | |
| SCHEMBL28027243 | 0.77 | ENPP1 (0.48) | ENPP1ESR1ESR2KDM4EMAPT | |
| SCHEMBL394890 | 0.75 | DHODH (0.50) | DHODHPDE10ALMNAKDM4EPOLB | |
| SCHEMBL624087 | 0.75 | LMNA (0.45) | ESR1DHODHPDE10ALMNAESR2 | |
| SCHEMBL12693813 | 0.74 | ERN1 (0.53) | LMNAKDM4EMAPTPOLBDCTPP1 | |
| SCHEMBL11375363 | 0.74 | GAA (0.46) | DHODHPDE10ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829295-A | Phenyl Linked Quinolinyl Modulators Of Ror-Gamma-T | 詹森药业有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105073729-A | Phenyl-linked quinolinyl modulators of ROR γ t | JANSSEN PHARMACEUTICA NV | 2015-11-18 | — | — | CN | disclosed |
| EP-1087790-A2 | USE OF A COMPOUND HAVING AFFINITY FOR THE BENZODIAZEPINE MITOCHONDRIAL RECEPTOR IN CANCER THERAPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999066958-A2 | USE OF A COMPOUND HAVING AFFINITY FOR THE BENZODIAZEPINE MITOCHONDRIAL RECEPTOR IN CANCER THERAPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1999-12-29 | — | — | WO | disclosed |