Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624087 | 0.98 | LMNA (0.45) | LMNADHODHPDE10AESR1ESR2 | |
| SCHEMBL2717330 | 0.79 | DHODH (0.51) | DHODHMAPTKMT2AMEN1KDM4E | |
| SCHEMBL15648140 | 0.79 | RXFP1 (0.52) | DHODHMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL311283 | 0.79 | KDM4E (0.44) | LMNADHODHPDE10ASMN1; SMN2MAPT | |
| SCHEMBL851828 | 0.79 | KDM4E (0.44) | LMNADHODHPDE10ASMN1; SMN2MAPT | |
| SCHEMBL3743372 | 0.78 | LMNA (0.71) | LMNADHODHPDE10ASMN1; SMN2MAPT | |
| SCHEMBL4060310 | 0.77 | KDM4E (0.43) | LMNADHODHPDE10ASMN1; SMN2MAPT | |
| SCHEMBL27797272 | 0.77 | KDM4E (0.43) | LMNADHODHPDE10ASMN1; SMN2MAPT | |
| SCHEMBL7761646 | 0.77 | ENPP1 (0.51) | LMNADHODHPDE10AESR1ESR2 | |
| SCHEMBL29636195 | 0.77 | ERN1 (0.47) | LMNADHODHPDE10AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199924-B2 | Process for the preparation of urethanes | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2603319-B1 | PROCESS FOR THE PREPARATION OF URETHANS | BAYER IP GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| US-20130303740-A1 | METHOD FOR PRODUCING URETHANES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-14 | — | — | US | disclosed |
| EP-2603319-A1 | METHOD FOR PRODUCING URETHANES | Bayer Intellectual Property GmbH (DE) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020028-A1 | METHOD FOR PRODUCING URETHANES | BAYER MATERIALSCIENCE AG (DE) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303740-A1 | METHOD FOR PRODUCING URETHANES | SOD1, AOC2, DUOX2 | LMNA 1462/4885DHODH 1942/4885PDE10A 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.