SCHEMBL7761684

SCHEMBL7761684

NC(=O)OC(CCC(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.47
CYP1A2 P05177 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GSR P00390 1/20 0.46
GRIK1 P39086 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK2 Q13002 1/20 0.46
GRIK3 Q13003 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28897504 0.78 FOLH1 (0.51) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL28969462 0.77 CYP1A2 (0.54) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL465915 0.75 TET2 (0.56) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL1258716 0.75 TET2 (0.56) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL6263449 0.75 FOLH1 (0.45) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL17165688 0.75 FOLH1 (0.45) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL14508863 0.75 FOLH1 (0.45) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL30424773 0.75 FOLH1 (0.49) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL11008799 0.75 TET2 (0.48) FOLH1CYP1A2GRM8GRM6GRIN2D
SCHEMBL17165685 0.74 LMNA (0.46) FOLH1TSHRLMNAPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001072767-A1 DEHYDROEPIANDROSTERONE DERIVATIVES, PREPARATION METHOD AND USES THEREOF, IN PARTICULAR FOR COSMETICS L'OREAL (FR) 2001-10-04 WO disclosed