SCHEMBL7761855

SCHEMBL7761855

NC(=O)c1ccc(Oc2cccc(N)c2)cc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.53
ALDH1A1 P00352 4/20 0.49
PARP10 Q53GL7 3/20 0.49
TNKS O95271 1/20 0.49
PARP15 Q460N3 1/20 0.49
PARP14 Q460N5 1/20 0.49
TNKS2 Q9H2K2 1/20 0.49
PARP2 Q9UGN5 1/20 0.49
ATM Q13315 1/20 0.48
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
MITF O75030 1/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46
KMT2A Q03164 1/20 0.46
NLRP1 Q9C000 1/20 0.46
NOD2 Q9HC29 1/20 0.46
POLB P06746 1/20 0.44
HSP90AA1 P07900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7764582 0.87 MAOB (0.53) MAOBALDH1A1PARP10TNKSPARP15
SCHEMBL27491890 0.87 PARP10 (0.58) MAOBALDH1A1PARP10TNKSPARP15
SCHEMBL7767012 0.85 PARP10 (0.59) MAOBALDH1A1PARP10TNKSPARP15
SCHEMBL6630317 0.80 PARP10 (0.75) MAOBALDH1A1PARP10TNKSPARP15
SCHEMBL9648190 0.79 MAOB (0.59) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL15053820 0.78 PARP10 (0.72) MAOBALDH1A1PARP10TNKSPARP15
SCHEMBL7099416 0.77 NR4A1 (0.71) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL204267 0.76 MAOB (0.86) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL29363390 0.76 MAOB (0.86) MAOBALDH1A1ATMMAPTSMN1; SMN2
SCHEMBL29352463 0.76 MAOB (0.86) MAOBALDH1A1ATMMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5115089-A Heat resistant polymers for electrical insulation, protective coatings for electronics formed by reaction of tetracarboxylic dianhydrides and diaminoamides and diamines HITACHI CHEMICAL CO., LTD. (JP) 1992-05-19 US claimed
EP-0758665-B1 Polyimides and optical parts obtained by using the same HITACHI CHEMICAL CO LTD (JP) 2001-06-20 EP disclosed
US-5837804-A MULTILAYER POLYIMIDES FOR TRANSPARENCY AND OPTICAL WAVEGUIDES HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-11-17 US disclosed
EP-0758665-A1 Polyimides and optical parts obtained by using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
EP-0308270-B1 Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof HITACHI CHEMICAL CO LTD (JP) 1993-12-08 EP disclosed
US-5115089-A Heat resistant polymers for electrical insulation, protective coatings for electronics formed by reaction of tetracarboxylic dianhydrides and diaminoamides and diamines HITACHI CHEMICAL CO., LTD. (JP) 1992-05-19 US disclosed
EP-0308270-A2 Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof Hitachi Chemical Co., Ltd. (JP) 1989-03-22 EP disclosed